A team of researchers led by Microsoft has identified a previously unrecognized vulnerability in the DNA‑screening systems that guard against biological threats. The gap, described as a "biological zero‑day," could allow AI‑designed toxins to slip past existing checks that flag DNA orders encoding known harmful proteins or viruses. While screening processes have evolved to catch DNA variants that produce the same dangerous proteins, the rapid advancement of AI‑generated protein designs may outpace current safeguards, prompting calls for updated detection methods.
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